Anger is in the genes

Being able to keep your cool or lose your temper is down to genes, according to a new study.
By Chris Irvine
Last Updated: 1:09AM BST 04 May 2009

Isolation of a gene called DARPP-32 helps explain why some people fly into a rage at the slightest provocation, while
others can remain calm.
More than 800 people were asked to fill in a questionnaire designed to study how they handle anger.

The German researchers also administered a DNA test to determine which of three versions of the DARPP-32 gene
people were carrying.
The gene affects levels of dopamine, a brain chemical linked to anger and aggression.
Those who had the "TT" or "TC" versions of the gene portrayed significantly more anger than those with the "CC" version.
The study, from the University of Bonn, also found that those who display more anger have less grey matter in the
amygdala, a part of the brain that helps keep our emotions balanced.
Martin Reuter, one of the researchers, who is a TC, said: "In other words, they are not able to control their feelings as well
as those without the mutation.
"I am not an angry person but I can get angry if it is important."
TT and TC versions are much more common in Western populations, with the researchers suggesting that demonstrations
of anger can help people get ahead in life.
"High degrees of anger are of course of low social desirability but a certain amount of dominance-related behaviour helps
to assert position in a social hierarchy," the researchers added.
Reporting in the journal Behavioural Brain Research, they added that genetics only account for around half of our
disposition towards anger, while DARPP-32 is one of several genes involved.
Earlier this year it was reported that showing anger rather than repressing emotions is the key to a successful professional
and personal life. The study by the Harvard Study of Adult Development found those who keep a check on their
frustrations are at least three times more likely to admit they have disappointing personal lives and have hit a glass ceiling
in their career.
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